Entrepreneurship in Europe is a priority as a a powerful driver of economic growth and job creation. The increasing demand for this skill and to reduce unemployment requires innovative ways to train. This paper present the StartUp model composed by the redefinition of Entrepreneurship in terms of competences and an Open Eductional Practice based on an Open Learning Architecture including steps of a quality lifecyle model for OER. This work has been done in the context of the European Project StartUp funded with support of the European Commission.